ABOUT PCOS 

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Patients with PCOS have been observed to have higher levels of androgens that interfere with the signals for ovulation that stem from the brain, this hampers the process of ovulation. The excess of androgens may also lead to formation of cysts which are small fluid filled sacs where eggs grow and mature and later stop developing and form clumps together.

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Insulin plays a role in the prognosis of PCOS, due to insulin resistance in patients suffering from PCOS  the blood glucose levels are high as a result more insulin is produced to control the blood glucose levels. Similarly to control the high levels of insulin in the body more androgens are secreted and thus a complex interplay of the hormones lead to PCOS (Valentia Rodriguez Paris, 2019). This cycle is difficult to disrupt and hence stands to be a challenge while trying to manage the condition.

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Apart from hormonal imbalances oxidative stress also partakes in the development of the syndrome via  increasing  insulin resistance by interfering with post insulin receptor signaling pathways, and conferring hyperandrogenemia by upgrading the activity of enzymes involved in steroidogenesis in ovaries  hence increasing androgen production. (PC Piotrowoski, 2005)